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The Sinatra Solution: New Hope for Preventing and Treating Heart Disease by Stephen T. Sinatra, M.D., F.A.C.C.

Metabolic Cardiology

Discover the triad of cardiac health - Coenzyme Q10, L-Carnitine, and D-Ribose. In combination, they help prevent and overcome heart disease, fibromyalgia, chronic fatigue, and Syndrome X.

It’s a fact, people with heart disease lack energy. The heart needs a large amount of oxygenated blood flow to continually meet its huge energy demands. That’s where the new triad of cardiac health comes in – Coenzyme Q10, L-Carnitine, and D-Ribose. The synergistic combination of these energy-supplying nutrients maximizes the amount of oxygen that the heart and skeletal muscle can extract from the blood by accelerating the rate at which cells convert nutrients to energy.

Board-certified cardiologist Dr. Stephen T. Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients have on the cardiovascular system. He guides you through the basics of energy metabolism and cardiac bioenergetics, and clearly explains the role of Coenzyme Q10, L-Carnitine, and D-Ribose in the body and specifically how they affect your heart health. He also provides concise and informative examples of case histories and scientific studies that are testament to the important contribution the supplemental use of these energy-supplying nutrients makes in the lives of people with heart disease every day.

While the main focus of The Sinatra Solution is on improving heart health, this new, (published in 2008), hardcover book also touches upon the positive effect the triad has on other diseases and disorders. You’ll learn that the supplemental use of these nutrients isn’t limited to healing a sick heart and preventing heart disease. Their energy-enhancing abilities work throughout the body, essentially charging up every body cell to function at optimal capacity.


Stephen T. Sinatra, M.D., is a board-certified cardiologist, a certified bioenergetic psychotherapist, and a certified nutrition and antiaging specialist. At his practice in Manchester, Connecticut, Dr. Sinatra integrates conventional medicine with complementary nutritional and psychological therapies to help heal the heart. He is an assistant clinical professor at the University of Connecticut School of Medicine, and is the author of several books, including Optimum Health, Heartbreak and Heart Disease, Heart Sense for Women, and Eight Weeks to Lowering Blood Pressure.

The information contained in The Sinatra Solution is based upon the research and personal and professional experience of Dr. Sinatra. It is not intended as a substitute for consulting with your physician or other healthcare provider. Any attempt to diagnose and treat an illness should be done under the direction of a healthcare professional.

If you suffer from heart disease, Dr. Stephen T. Sinatra has the solution you've been looking for: Maximize the amount of oxygen your heart extracts from your bloodstream by accelerating the rate at which your cells convert nutrients to energy.

This can be achieved by following Dr. Sinatra's energy-enhancing nutritional approach. This approach focuses on the supplemental use of three amazing bioenergetic nutrients: Coenzyme Q10, L-carnitine, and D-ribose.

The synergistic combination of these nutrients essentially charge up every body cell to function at optimal capacity. So, not only will you experience renewed heart health with all that energy, you'll also gain a greater sense of overall well-being.

Sample Recommendations:

High Blood Pressure

  • Multivitamin/mineral foundation program with 1 gram of fish oil
  • Coenzyme Q10: 180 - 360 mg
  • L-carnitine 500 - 1,000 mg
  • D-ribose 5 -10 grams
  • Magnesium 400 - 800 mg
  • Additional fish oil: 2 grams
  • Garlic: 1 gram
  • Hawthorn berry 1,000 - 1,500 mg
  • Note: Garlic and hawthorn berry have very similar action to ACE (angiotensin converting enzyme) inhibitors in lowering blood pressure.

Congestive Heart Failure

  • Multivitamin/mineral foundation program with 1 gram of fish oil
  • Coenzyme Q10: 300 - 360 mg
  • L-carnitine 2,000 - 2,500 mg
  • D-ribose 10 -15 grams
  • Magnesium 400 - 800 mg

Other recommendations include:

  • Age-management program
  • Stable Angina Pectoris
  • Cardiac Arrhythmia - Prevention of premature contractions, premature atrial contractions,and intermittent atrial fibrillation
  • Severe congestive heart failure, dilated cardiomyopathy, patients awaiting heart transplantation
  • Mitral valve prolapse
  • Fibromyalgia, chronic fatigue syndrome, or mitochondrial cytopathies
  • Syndrome X, insulin resistance, and type 2 diabetes
  • A program for professional or world-class athletes
  • Couch Potato Program



Author's Note to the Revised Edition xiii

Introduction by James C. Roberts, M.D., F.A.C.C. 1

  1. Integrative Cardiology 5
  2. Miracles in the Midst 19
  3. ATP: The Miracle of Life 29
  4. The Spark of Life: Coenzyme Q10 59
  5. L-Carnitine: The Energy Shuttle 101
  6. D-ribose: The Sugar of Life - the Missing Link 145
  7. Magnesium: the Unsung Hero 179
  8. The Sinatra Solution for Strengthening the Heart and Body 193
  9. Conclusion 211

Glossary 212

Resources 219

References 221

Index 245

About the Author 254

Hardback: Basic Health Publications, 254 pages

Index, preview, endorsements, and back cover reprinted with the exclusive permission of Basic Health Publications.