You know information on diet and weight loss fills an entire aisle at a book store. Here are the highlights.
Here are our recommendations:
These are the supplements and recommended dosage that will help you lose fat, maintain muscle mass, and give you natural energy for the days ahead.
Rejuvenation Science® Premium Weight-Loss Program:
+ may require more depending on diet.
# Glutamine, Acetyl L-Carnitine, and additional alpha-lipoic acid are optional
The Rejuvenation Science® Premium Weight-Loss package uses a variety of bottle sizes. This means that some bottles will contain a 1 to 2 month supply. The net result is that using the Rejuvenation Science Supplement package will cost you $137.96 per month, however your initial purchase will be for $159.98 (because you are buying more than a 1-month supply of some of the supplements).
These synergistic supplements help manage your appetite, maintain energy, and help manage your weight. Successful weight management requires exercise and a healthy lifestyle.
Research conducted at the Methodist DeBakey Heart Center in Houston identified a molecular link between obesity and inflammation. This research shows that a high fat diet draws inflammatory cells into fat tissue, which prevents the tissue from storing the fats we eat. When the tissue can not store these fats, they end up in the liver and muscle, which in turn causes weight-gain and diabetes.1
Inflammation is responsible for aging, many age-related illnesses and is related to how we store and metabolize fat in the body. Our cells use oxygen to produce energy and they generate free radicals as a byproduct of this metabolic function. Antioxidants scoop up free radicals, preventing the cellular degeneration within the body that causes further damage.
Rejuvenation Science® Maximum Vitality™ is a robust antioxidant multivitamin, containing antioxidant vitamins A, C, E, plus alpha- and R-lipoic acid, Lycopene, Lutein, Astaxanthin, Green Tea, Gamma-E, milk thistle, hawthorn berry, curcumin, and proanthocyanidins from grape seed.
Omega-3 polyunsaturated fatty acids (PUFAs) from fish oil have anti-inflammatory characteristics and promote weight loss. Omega-3’s accelerate body fat loss, elevate mood, stabilize blood sugar levels, lower insulin levels, and decrease appetite.2,3 The recommended dosage varies depending upon how much weight loss is desired. The recommended range is 3 to 9 softgels per day.
Omega-6 fatty acids from vegetable oil are pro-inflammatory and promote weight gain.
The ideal balance of Omega 6 to Omega-3 is a ratio of 2:1 or 1:1. The standard American diet now contains a highly inflammatory ratio of 24:1 Omega-6 to Omega-3. Pro-inflammatory Omega-6 oils are found in margarine, vegetable oil (corn, safflower, canola, etc.), salad dressing, fried, and prepared foods, and even farm-raised (corn meal-fed) fish. Almost every fried food or snack food is cooked in omega-6 oils, because they are both less expensive and have a longer shelf-life.
CLA (Conjugated Linoleic Acid) helps convert fat to lean muscle mass. Intake of CLA - naturally found in beef, lamb, turkey, and milk products – has decreased significantly, while obesity in the U.S. has increased. When animals are raised on prepared corn feed, they take on more inflammatory characteristics and contain less than half the CLA of range-fed beef.
Short-term studies have shown that CLA supplementation improves body composition. Now Jean-Michel Gaullier’s “Efficacy and safety of one-year supplementation with conjugated linoleic acid in moderate overweight” demonstrated that CLA reduced body fat by nine percent and increased lean muscle by two percent in a 2-year study.4
Weight loss is a function of cellular energy production, among other factors. Many diet products contain stimulants which unnaturally stimulate thermogenesis - the production of energy and heat. These may work in the short-term, but leave you feeling tired and depleted when they wear off.
Metabolic Optimizer™ components - coenzyme Q10, carnitine, acetyl l-carnitine, alpha-lipoic acid and ribose provide the nutrients and co-factors which naturally help your body optimize its cellular energy production. Not only do these nutrients provide greater energy and endurance, and a greater ability to lose body fat, they help prevent the energy decline seen in aging cells.
The food you eat and your exercise demands will work in conjunction with your cellular energy production to either lead to weight loss or gain. Your Doctor may recommend a special diet and exercise and choose which Metabolic Optimizer™ components are best for you.
L-Carnitine is a water-soluble nutrient that helps support healthy fat utilization and energy production. For carnitine and acetyl l-carnitine to have optimum effect, adequate omega-3 fatty acids need to be present in the diet. Carnitine optimizes energy formation and an active metabolism. Small amounts of carnitine are obtained from foods, such as meat and dairy products, but to get an abundant supply, supplementation is necessary.
In order for fat to be turned into fuel, it has to be carried into the mitochondria, the cell’s energy furnace.5,6
The principle function of L-Carnitine is to facilitate the transport of long-chain fatty acids across the inner mitochondrial membrane to begin the cellular metabolic (energy production) process. L-Carnitine is the only carrier that can perform this function, thus its abundant presence is critical to life.
Coenzyme Q10 helps increase energy levels and overall sense of vitality. CoQ10 is a powerful antioxidant and anti-inflammatory. Like acetyl l-carnitine, CoQ10 assists in mitochondrial energy production. Working synergistically with the other metabolic optimizers – carnitine, acetyl l-carnitine, and alpha-lipoic acid, CoQ10 enhances the metabolism, providing greater energy and endurance, and a greater ability to lose body fat, while preventing the energy decline seen in aging cells. CoQ10 also works synergistically with other antioxidants to recycle antioxidants – vitamins C, E, and glutathione - and help regulate blood sugar and enhance insulin sensitivity.
Now enhanced with Ubiquinol, the more powerful, antioxidant form of CoQ10, which represents 90% of the CoQ10 which naturally occurs in the body. Provides enhanced clinical benefits.
Alpha Lipoic Acid is a potent antioxidant and anti-inflammatory, both water- and fat-soluble. It is part of the enzyme complex intimately involved in energy production of the cell. Alpha-lipoic acid helps convert carbohydrates, fats and protein into energy by helping take glucose into the cells. In addition to carnitine and acetyl L-carnitine, alpha-lipoic acid also helps preventing glycation. As an antioxidant, alpha-lipoic acid works with coenzyme Q10, carnitine and acetyl l-carnitine to protect and rejuvenate the mitochondria.
An aging cell is characterized by decreased energy production. Alpha-lipoic acid works synergistically with other antioxidants to allow the cells to repair themselves in the same way that young cells do. Robust energy production in the cells allow efficient energy usage, and thus contribute to fat loss.
Acetyl L-Carnitine is a derivative of l-carnitine. ALC is not found in food, however, the addition of the acetyl group allows ALC to pass through the blood-brain barrier. It enables dietary fats to better be converted to energy and muscle.
Both ALC and carnitine are important in weight-loss because they act as natural anti-inflammatories and aid in transportation of fats into the mitochondria to be burned to generate energy. They also enhance the sensitivity of insulin receptors, helping to decrease blood sugar and circulating levels of insulin. Both ALC and carnitine help prevent glycation.5
Chromium is an essential nutrient that promotes normal blood sugar levels and normal insulin function. It is essential for proper protein, fat and carbohydrate metabolism. In this way, it is important for energy production and also plays a key role in regulating appetite, reducing sugar cravings and lowering body fat. Thus chromium plays a critical role in healthy body weight and lean body mass.
In clinical studies, niacin-bound chromium, known as chromium polynicotinate, has been demonstrated to be a superior form of chromium. Animal studies have shown that niacin-bound chromium increased average lifespan by 20% compared with placebo. The potential for the relationship between caloric deprivation and normal glucose and insulin levels for increasing lifespan is yet to be proven.8
L-Glutamine is the body’s most abundant amino acid. It plays an important role in keeping muscles functioning properly and helping to reduce muscle deterioration. When overweight, the body breaks down the muscle tissue to get extra glutamine, so an overweight person tends to lose muscle mass. Having enough glutamine ensures both weight loss and muscle mass retention.9
Glutamine nourishes the cells that line the stomach, intestines and digestive track. These cells use glutamine as a fuel. In combination with other amino acids – N-Acetyl-Cysteine and glycine, glutamine promotes synthesis of glutathione in the liver. Glutamine will reduce cravings for high-glycemic carbohydrates, making weight-loss easier.
1. Press release: Link Between Obesity and Inflammation, Methodist DeBakey Heart Center, Houston TX. November 2006.
2. Ruzickova J, Rossmeisl M, Prazak T, Flachs P, Sponarova J, Veck M, Tvrzicka E, Bryhn M, Kopecky J: Omega-3 PUFA of marine origin limit diet-induced obesity in mice by reducing cellularity of adipose tissue. Lipids 2004, 39:1177-1185.
3. Browning LM. N-3 polyunsaturated fatty acids, inflammation and obesity-related disease. Proc Nutr Soc. 2003 May;62(2):447-53.
4. Jean-Michel Gaullier, Johan Halse, Kjetil Høye, Knut Kristiansen, Hans Fagertun, Hogne Vik, and Ola Gudmundsen. Supplementation with Conjugated Linoleic Acid for 24 Months Is Well Tolerated by and Reduces Body Fat Mass in Healthy, Overweight Humans
J. Nutr. 2005 135: 778-784.
5. Mingrone G. Carnitine in type 2 diabetes. Ann NY Acad Sci. 2004 Nov;1033:99-107. Review.
6. Brandsch C, Eder K. Effect of L-carnitine on weight loss and body composition of rats fed a hypocaloric diet. Ann Nutr Metab. 2002;46(5):205-10.
7. Sarah Molyneux, Christopher Florkowski, Michael Lever, Peter George. The bioavailability of coenzyme Q10 supplements available in New Zealand differs markedly. Journal of the New Zealand Medical Association, 08-October-2004, Vol 117 No 1203.
8. Preuss HG, Grojec Pl, Lieberman S, Anderson RA. Effects of different chromium compounds on blood pressure and lipid peroxidation in spontaneously hypertensive rats. Clinical Nephrology 1997;47(5):325-30.
9. Opara EC, Petro A, Tevrizian A, Feinglos MN, Surwit RS. L-Glutamine supplementation of a high fat diet reduces body weight and attenuates hyperglycemia and hypertension in C57BL/6J mice. J Nutr. 1996 Jan;126(1):273-9.